Dynamic urinary proteomic analysis in a Walker 256 intracerebral tumor model

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Dynamic changes of urine proteome in a Walker 256 tumor‐bearing rat model

Despite advances in cancer treatments, early diagnosis of cancer is still the most promising way to improve outcomes. Without homeostatic control, urine reflects systemic changes in the body and can potentially be used for early detection of cancer. In this study, a tumor-bearing rat model was established by subcutaneous injection of Walker 256 cells. Urine samples from tumor-bearing rats were ...

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Tumor Growth Characteristics of the Walker 256 AR Tumor, a Regressive Variant of the Rat Walker 256 A tumor

The present study aimed at characterizing the subcutaneous development of the Walker 256 (W256) AR tumor, a regressive variant of the rat W256 A tumor. Wistar rats were injected subcutaneously with 4x10 W256 A or W256 AR tumor cells. The development of tumors was evaluated daily by percutaneous measurements. None of the W256 A tumors (n=20) regressed, but 62% of the W256 AR tumor-bearing rats (...

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Walker Carcinoma 256

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Serum polysaccharide levels in rats bearing the Walker 256 tumor.

Previous work on human subjects (9) has shown that the polysaccharide associated with serum proteins is significantly elevated in malig nancy. Little is known concerning the correlation between this elevation and the cancerous condi tion. Work in this laboratory has shown that the serum polysaccharide of dogs is increased in sev eral types of experimental inflammation (7). An elevation also occ...

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ژورنال

عنوان ژورنال: Cancer Medicine

سال: 2019

ISSN: 2045-7634,2045-7634

DOI: 10.1002/cam4.2240